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In addition to the surgery, four patients were treated with gestagens.Biopsies or excisions from the tumors were examined microscopically and immunohistochemically (IHC). By IHC examination, the sex cord-like component was calretinin-positive, while the stromal component was positive for CD10 and negative for h-caldesmon in all the cases studied.Uterine tumors resembling ovarian sex-cord tumors (UTROSCT) cause difficulties, both with respect to diagnosis as well as to the nomenclature.
During 60 months of follow-up no evidence of recurrence was observed.
We describe a rare case of endometrial stromal tumor with sex-cord-like differentiation successfully treated by resectoscopic surgery and conservation of the uterus, in an infertile patient affected by metrorrhagia.
This procedure resulted in a pregnancy immediately after treatment and in a successful delivery.
These tumors were classified into two groups with considerable practical relevance because clinical behaviour of uterine tumor resembling ovarian sex cord tumor (UTROSCT) differs widely from its closely related endometrial stromal tumors with sex-cord-like elements (ESTSCLE).
Treatment and prognosis of these tumors are unresolved issues because of the exiguous number of reported cases.